Characterization of glucosylceramides in Pseudallescheria boydii and their involvement in fungal differentiation

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Characterization of Scedosporium apiospermum Glucosylceramides and Their Involvement in Fungal Development and Macrophage Functions

Scedosporium apiospermum is an emerging fungal pathogen that causes both localized and disseminated infections in immunocompromised patients. Glucosylceramides (CMH, GlcCer) are the main neutral glycosphingolipids expressed in fungal cells. In this study, glucosylceramides (GlcCer) were extracted and purified in several chromatographic steps. Using high-performance thin layer chromatography (HP...

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Biochemical characterization of potential virulence markers in the human fungal pathogen Pseudallescheria boydii.

The ubiquitous Pseudallescheria boydii (anamorph Scedosporium apiospermum) is a saprophytic filamentous fungus recognized as a potent etiologic agent of a wide variety of infections in immunocompromised as well as in immunocompetent patients. Very little is known about the virulence factors expressed by this fungal pathogen. The present review provides an overview of recent discoveries related ...

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[Pseudallescheria boydii fungal endophthalmitis. 6 years after trabeculectomy].

A case is reported of a 67-year-old female patient, in whom a fungal endophthalmitis occurred 6 years after trabeculectomy. Pseudallescheria Boydii was isolated. This organism is a rare cause of infection. In the literature only 14 cases of keratitis and 8 cases of endophthalmitis have been reported. Miconazole is the therapy of choice. However in 55% of the published cases, (as in the one repo...

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Meningitis caused by Pseudallescheria boydii.

We present a 43-year-old immunocompetent man who developed meningitis caused by Pseudallescheria boydii. The patient had no history of near drowning, trauma, steroid administration, operations or any other underlying systemic disease. He presented with intermittent fever associated with headache, bilateral eye pain, and vomiting. Progressive hydrocephalus was noted during the course of the dise...

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Pseudallescheria Boydii pneumonia in an immunocompetent host

BACKGROUND Pseudallescheria boydii pneumonia is rarely reported among immunocompetent patients. CASE REPORT We report a case of a 62 year old white female with pseudallescheria boydii pneumonia. The patient was non-immunocompromised, had a history of mycobacterium avium complex (MAC) infection prior to presentation. After successful response to initial antitubercular therapy, the patient deve...

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ژورنال

عنوان ژورنال: Glycobiology

سال: 2002

ISSN: 0959-6658,1460-2423

DOI: 10.1093/glycob/12.4.251